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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
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Radiological manifestations of melioidosis

K S Lim1, V H Chong

  • 1Department of Radiology, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BA 1710, Brunei Darussalam. kianslim@gmail.com

Clinical Radiology
|January 28, 2010
PubMed

Insights

Melioidosis, a severe bacterial infection caused by Burkholderia pseudomallei, can affect multiple organs. Radiological imaging aids diagnosis, with a "honeycomb" liver abscess appearance being characteristic.

Area of Science:

  • Infectious Diseases
  • Radiology
  • Microbiology

Background:

  • Melioidosis is a severe, often fatal infection caused by Burkholderia pseudomallei, an environmental bacterium.
  • It is endemic in Southeast Asia and Northern Australia but increasingly reported globally.
  • The infection can affect virtually any organ system.

Purpose of the Study:

  • To describe the diverse radiological manifestations of melioidosis across various organs.
  • To enhance awareness among clinicians regarding imaging findings to facilitate early diagnosis.
  • To highlight the importance of radiological imaging in the diagnostic workup of melioidosis.

Main Methods:

  • This pictorial essay reviews radiological findings from confirmed melioidosis cases.
  • It includes imaging examples of melioidosis affecting multiple organ systems.
  • The focus is on characteristic and suggestive imaging features.

Main Results:

  • Melioidosis can present with varied radiological findings, often without pathognomonic signs.
  • Simultaneous involvement of multiple organs is a common characteristic.
  • A "honeycomb" appearance in large liver abscesses is a distinctive feature.

Conclusions:

  • Radiological imaging is crucial for diagnosing melioidosis and guiding treatment.
  • Familiarity with melioidosis's diverse imaging spectrum aids in early detection.
  • While not always specific, certain findings like "honeycomb" liver abscesses are highly suggestive.

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