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Updated: Jun 16, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Correlates of insulin injection omission
Mark Peyrot1, Richard R Rubin, Davida F Kruger
1Department of Sociology, Loyola University Maryland, Baltimore, Maryland, USA. mpeyrot@loyola.edu
Many people with diabetes intentionally skip insulin injections due to factors like pain, embarrassment, and daily interference. Identifying these risks is crucial for improving treatment adherence and patient outcomes.
Area of Science:
- Endocrinology
- Diabetes Management
- Patient Adherence Research
Background:
- Insulin therapy is fundamental for managing type 1 and type 2 diabetes.
- Patient adherence to insulin injection regimens can be suboptimal.
- Understanding reasons for intentional insulin omission is critical for effective diabetes care.
Purpose of the Study:
- To identify demographic, disease-specific, and injection-related factors associated with the frequency of intentionally skipping insulin injections.
- To explore differences in these factors between patients with type 1 and type 2 diabetes.
Main Methods:
- An online survey was administered to 502 U.S. adults using insulin injections for diabetes.
- Multiple regression analysis was employed to determine independent risk factors for insulin omission.
Main Results:
- Over half of respondents reported intentional insulin omission, with 20% reporting regular omission.
- Key risk factors included younger age, lower income, higher education, type 2 diabetes, poor diet adherence, more frequent injections, and injection-related interference, pain, and embarrassment.
- Risk factors varied by diabetes type, with diet nonadherence more prevalent in type 1 and age, education, income, pain, and embarrassment in type 2 diabetes.
Conclusions:
- A significant number of patients intentionally omit insulin injections, necessitating identification and awareness of associated risk factors.
- Addressing injection-related issues like interference, pain, and embarrassment can improve adherence.
- Interventions targeting identified risk factors may enhance insulin regimen adherence and improve clinical outcomes.
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