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Related Experiment Video

Updated: Jun 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

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Published on: June 2, 2014

[Migraine therapy in general practice 2006].

Hartmut Göbel1

  • 1Neurologisch-verhaltensmedizinische Schmerzklinik Kiel. hg@schmerzklinik.de

MMW Fortschritte Der Medizin
|January 29, 2010
PubMed
Summary

Migraine treatment involves prophylaxis and abortive care using drug and non-drug options. Triptans are effective for severe attacks but have contraindications and are not for emergencies.

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Migraine management requires both preventative (prophylaxis) and acute (abortive) treatment strategies.
  • Both pharmacological and non-pharmacological interventions are available for migraine therapy.

Purpose of the Study:

  • To review the available therapeutic options for migraine management.
  • To highlight the characteristics and contraindications of triptans used in severe migraine attacks.

Main Methods:

  • Literature review of migraine treatment modalities.
  • Analysis of drug and non-drug strategies for prophylaxis and abortive treatment.
  • Evaluation of triptan efficacy, pharmacokinetics, and safety profiles.

Main Results:

  • Analgesics and antiemetics are used for mild attacks; triptans are essential for severe attacks.

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  • Triptans exhibit variability in efficacy, tolerance, onset, and duration, with diverse pharmaceutical forms available.
  • Contraindications for triptans include vascular diseases and pregnancy; they are unsuitable for emergency care.

    • Conclusions:

    • Migraine treatment is multifactorial, requiring tailored approaches for mild and severe attacks.
    • Triptans represent a key therapeutic class for severe migraines but necessitate careful patient selection due to contraindications.
    • Comprehensive understanding of treatment options and triptan specificities is crucial for effective migraine management.