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Published on: June 14, 2019
[Human papillomavirus detection in clear cell carcinoma of the cervix]
Yi-fan Guo1, Ai-jun Liu, Xiao-li Wang
1Department of Obstetrics and Gynaecology, PLA General Hospital, Beijing 100853, China.
Objective:
To investigate the infection of the high risk human papillomavirus (HPV) in the specimen of the clear cell carcinoma of the cervix.
Methods:
We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimens from a 37-year-old patient with clear cell carcinoma of the cervix and detected the HPV genotype with the nested PCR.
Results:
We identified HPV18, a high-risk genotype, in the specimens.
Conclusion:
The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of clear cell carcinoma of the cervix (CCCC) with a high accuracy and sensitivity.
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