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Updated: Jun 16, 2026

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes
Published on: May 1, 2021
Modeling of mosquitoes with dominant or recessive transgenes and Allee effects
1Department of Mathematical Sciences, University of Alabama in Huntsville, Huntsville, AL 35899, United States. li@math.uah.edu
Abstract:
To study the impact of releasing transgenic mosquitoes on malaria transmission, we formulate discrete-time models for interacting wild and transgenic mosquitoes populations, based on systems of difference equations. We start with models including all homozygous and heterozygous mosquitoes. We then consider either dominant or recessive transgenes to reduce the 3-dimensional model systems to 2-dimensional systems. We include density-dependent vital rates and incorporate Allee effects in the functional mating rates. Dynamics of these models are explored by investigating the existence and stability of boundary and positive fixed points. Numerical simulations are provided and brief discussions are given.
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