Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Framing Effects03:26

Framing Effects

Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in different ways based on the...
Frames01:30

Frames

Frames are essential components of various mechanical and structural systems used daily. These structures are known for their stability and ability to bear heavy loads. A frame is constructed using two-force and multi-force members, interconnected using pin joints. In contrast, trusses are made entirely of two-force members.
Frames are versatile and widely used in various applications such as structural supports for beams and columns, automobile chassis construction, and in the construction...
Frames: Problem Solving I01:24

Frames: Problem Solving I

Consider a jib crane with an external load suspended from the pulley. The dimensions of the crane members are shown in the figure. A systematic analysis of the frame structure is required to determine the reaction forces at the pin joints, assuming that the pulleys are frictionless.
Frames: Problem Solving II01:26

Frames: Problem Solving II

Consider a hydraulic hoist supporting a load of 1 kN. Assuming a simplified schematic representation of this frame structure, the force acting on BD and BF members can be determined.
Conditions on Early Earth02:06

Conditions on Early Earth

Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and hydrogen into the primordial atmosphere. However, organisms with the characteristics of life were not initially present on earth. Scientists have used experimentation to determine how organisms evolved that could grow, reproduce, and maintain an internal environment.
Conditions on Early Earth02:06

Conditions on Early Earth

Around 4 billion years ago, oceans began to condense on earth while volcanic eruptions released nitrogen, carbon dioxide, methane, ammonia, and hydrogen into the primordial atmosphere. However, organisms with the characteristics of life were not initially present on earth. Scientists have used experimentation to determine how organisms evolved that could grow, reproduce, and maintain an internal environment.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Owned dog population size and ownership patterns in Costa Rica.

Frontiers in veterinary science·2022
Same author

Advances in alternative non-animal testing methods represent a way to find new treatments for patients.

European journal of internal medicine·2017
Same author

Ending the use of animals in toxicity testing and risk evaluation.

Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees·2015
Same author

Role of dog sterilisation and vaccination in rabies control programmes.

The Veterinary record·2014
Same author

Preface. The Three Rs at the begining of the 21st century.

Alternatives to laboratory animals : ATLA·2013
Same author

Biology teachers' attitudes to dissection and alternatives.

Alternatives to laboratory animals : ATLA·2013

Related Experiment Video

Updated: Jun 16, 2026

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos
07:29

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

FRAME: the early days.

Andrew N Rowan1

  • 1The Humane Society of the United States, 2100 L Street NW, Washington, DC, USA. arowan@humanesociety.org

Alternatives to Laboratory Animals : ATLA
|January 29, 2010
PubMed
Summary

This article details the early history of FRAME, highlighting founder Mrs. Hegarty's influence on its scientific strategy and development. It covers key contributors and the organization's foundational approach.

Area of Science:

  • The article falls under the domain of organizational history and scientific administration.
  • It specifically focuses on the establishment and early strategic development of FRAME.

Background:

  • Reviews the initial phase of the Fund for the Replacement of Animals in Medical Experiments (FRAME).
  • Highlights the pivotal role of founder Mrs. Hegarty and other early collaborators.
  • Examines the foundational period of FRAME's scientific endeavors.

Discussion:

  • Analyzes FRAME's strategic direction during its nascent stages.
  • Explores the impact of Mrs. Hegarty's personal background on the organization's scientific approach.
  • Discusses the collaborative efforts that shaped FRAME's early trajectory.

Key Insights:

  • Founder Mrs. Hegarty's background significantly influenced FRAME's strategic scientific approach.

More Related Videos

Light Sheet Microscopy Imaging and Mounting Strategies for Early Zebrafish Embryos
08:33

Light Sheet Microscopy Imaging and Mounting Strategies for Early Zebrafish Embryos

Published on: July 19, 2024

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy
11:17

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy

Published on: September 11, 2014

Related Experiment Videos

Last Updated: Jun 16, 2026

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos
07:29

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

Light Sheet Microscopy Imaging and Mounting Strategies for Early Zebrafish Embryos
08:33

Light Sheet Microscopy Imaging and Mounting Strategies for Early Zebrafish Embryos

Published on: July 19, 2024

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy
11:17

Fundamental Technical Elements of Freeze-fracture/Freeze-etch in Biological Electron Microscopy

Published on: September 11, 2014

  • Early contributors played a crucial role in establishing FRAME's operational and scientific foundations.
  • The article provides a unique perspective from FRAME's first Scientific Administrator.
  • Outlook:

    • Understanding FRAME's historical context is vital for appreciating its current scientific standing.
    • The foundational strategies continue to inform approaches to the replacement of animals in medical experiments.
    • Further research could explore the long-term impact of early leadership on scientific organizations.