Related Experiment Video
Updated: Aug 15, 2026

09:05
Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice
Published on: February 22, 2018
Intrathecal morphine for thymectomy in a morbidly obese patient with myasthenia gravis
1Tulane University School of Medicine, New Orleans.
Abstract:
Postoperative respiratory management in a patient with myasthenia gravis is a difficult problem because of underlying muscle weakness, residual effects of anesthesia, and incisional pain. Use of intrathecal morphine reduces the amount of inhalation agent needed and provides analgesia for the first postoperative day, leading to a prompt, smooth emergence and easy extubation.
Related Concept Videos
Myasthenia Gravis: Overview and Treatment
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Skeletal Muscle Relaxants: Therapeutic Uses
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx as...

