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Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Myasthenia Gravis: Overview and Treatment

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Parkinson's Disease: Treatment

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Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Related Experiment Video

Updated: Jun 16, 2026

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)
08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)

Published on: December 26, 2015

[Current treatment for multiple sclerosis].

Caroline Papeix1, Catherine Lubetzki, Olivier Lyon-Caen

  • 1Fédération des maladies du système nerveux, groupe hospitalier Pitié-Salpêtrière, 75651 Paris cedex 13, France. caroline.papeix@psl.aphp.fr

Presse Medicale (Paris, France : 1983)
|January 29, 2010
PubMed
Summary
This summary is machine-generated.

Current multiple sclerosis (MS) treatments include immunomodulatory agents and monoclonal antibodies. These therapies effectively reduce relapses and MRI-detected lesions, with new approaches like remyelination offering future hope.

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Last Updated: Jun 16, 2026

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis (MS)
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Area of Science:

  • Neurology
  • Immunology
  • Pharmacology

Context:

  • Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
  • Established treatments for MS include immunomodulatory agents and newer monoclonal antibody therapies.
  • Ongoing research explores novel therapeutic strategies for MS management.

Purpose:

  • To review current and emerging pharmacological treatments for multiple sclerosis.
  • To highlight the efficacy of existing therapies in managing MS relapses and disease progression.
  • To discuss future therapeutic directions, including remyelinating and neuroprotective approaches.

Summary:

  • Interferon beta (IFN beta) and Glatiramer acetate are effective immunomodulatory agents for MS, reducing relapses and MRI-visible lesions.
  • Natalizumab, a monoclonal antibody, has demonstrated efficacy in reducing short-term disability and relapse rates in relapsing MS.
  • Clinical trials are evaluating additional monoclonal antibodies and immunosuppressors, alongside promising remyelinating and neuroprotective strategies.

Impact:

  • Provides an overview of the current therapeutic landscape for multiple sclerosis.
  • Informs clinicians and researchers about the benefits of established and investigational MS treatments.
  • Highlights the potential of future therapies to offer new perspectives for MS patients.