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Updated: Mar 31, 2026

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
Prevention and management of pain and stress in the neonate
Insights
Neonatal pain is a significant concern for healthcare professionals. This statement provides guidance on assessing and managing pain and stress in newborns to improve outcomes.
Area of Science:
- Neonatal care
- Pediatric pain management
- Clinical practice guidelines
Background:
- Neonates, including preterm infants, experience pain and stress.
- Pain and stress in neonates can lead to adverse physiological and behavioral outcomes.
- Effective assessment and management strategies are crucial for neonatal well-being.
Purpose of the Study:
- To raise awareness of neonatal pain perception.
- To establish a physiological rationale for neonatal pain assessment and management.
- To provide evidence-based recommendations for minimizing neonatal pain and stress.
Main Methods:
- Review of current literature on neonatal pain and stress.
- Development of clinical recommendations based on physiological principles and empirical evidence.
- Guidance for healthcare professionals in assessing and managing neonatal pain.
Main Results:
- Neonates possess the physiological capacity to experience pain.
- Standardized assessment tools and interventions can effectively manage neonatal pain.
- Reducing exposure to noxious stimuli is paramount in neonatal care.
Conclusions:
- Healthcare professionals must recognize and address neonatal pain.
- Effective pain management in neonates is achievable through appropriate interventions.
- Adherence to recommended practices can mitigate adverse outcomes associated with neonatal pain and stress.
Abstract:
This statement is intended for health care professionals caring for neonates (preterm to one month of age). The objectives of this statement are to: increase awareness that neonates experience pain; provide a physiological basis for neonatal pain and stress assessment and management by health care professionals; make recommendations for reduced exposure of the neonate to noxious stimuli and to minimize associated adverse outcomes; and recommend effective and safe interventions that relieve pain and stress.
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