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Updated: Jun 16, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Pulmonary manifestations of inflammatory bowel disease]
O Bachmann1, F Länger, J Rademacher
1Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Carl-Neuberg-Strasse 1, 30625, Hannover, Deutschland. bachmann.oliver@mh-hannover.de
Abstract:
Pulmonary disease is a rare complication of inflammatory bowel disease. Airway inflammation, interstitial lung disease and several other manifestations have been described, and typical symptoms are productive cough, chest pain, and progressive dyspnea. Due to the frequency of preceding pulmonary disease and the common temporal dissociation regarding intestinal disease, pulmonary manifestations of inflammatory bowel disease are at high risk of being overlooked. If suspected, early work-up including CT scan and bronchoscopy should be initiated, since the natural course often involves rapidly progressive lung damage. The best therapeutic results have been obtained with topic and systemic steroids, while classic immunosuppressants are commonly not efficacious. Several case reports describe a beneficial effect of infliximab.
Insights
Pulmonary disease is a rare complication of inflammatory bowel disease (IBD). Early diagnosis and treatment with steroids or infliximab are crucial for managing lung damage in IBD patients.
Area of Science:
- Pulmonology
- Gastroenterology
- Internal Medicine
Context:
- Inflammatory bowel disease (IBD) can manifest with rare pulmonary complications.
- Symptoms include cough, chest pain, and dyspnea, often with delayed onset relative to intestinal symptoms.
- Pulmonary involvement in IBD is frequently overlooked due to its rarity and temporal dissociation.
Purpose:
- To review the spectrum of pulmonary manifestations in IBD.
- To highlight diagnostic challenges and recommend early work-up strategies.
- To discuss current and emerging therapeutic options for IBD-associated lung disease.
Summary:
- Pulmonary disease in IBD encompasses airway inflammation and interstitial lung disease.
- Diagnosis requires high clinical suspicion, CT scans, and bronchoscopy.
- Steroids are primary treatment; immunosuppressants are often ineffective, but infliximab shows promise.
Impact:
- Timely recognition and intervention can prevent progressive lung damage.
- Understanding these complications improves patient outcomes in IBD.
- This review aids clinicians in diagnosing and managing rare pulmonary manifestations of IBD.
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