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Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Antibacterial constituents from the roots of Erythrina herbacea against methicillin-resistant Staphylococcus aureus
Hitoshi Tanaka1, Masaru Sudo, Tomoko Kawamura
1Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya, Japan. hitoshi@ccmfs.meijo-u.ac.jp
Abstract:
Two new compounds, erybacin A (1) and erybacin B (2), together with 10 known compounds (3- 12), were isolated from the roots of Erythrina herbacea. Their structures were established on the basis of spectroscopic analyses. Erybacin A is a rare, naturally occurring 1-hydroxy-1,3-diphenylpropan-2-one derivative. The isolated compounds were evaluated for their antibacterial activity against 13 strains of methicillin-resistant Staphylococcus aureus (MRSA). The new compound 2 showed a potent bactericidal activity against MRSA.
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