Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Automated Microbial Diagnostics01:24

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
Methods of Classification and Identification01:28

Methods of Classification and Identification

Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chiral Au@Ag Core-Shell Nanoparticles for Enantioselective SERS Detection of Bio-Relevant Chiral Molecules.

ACS nanoscience Au·2026
Same author

Ultrafast Near-Field Dynamics in Silver Nanowires Driven by Few-Cycle Short-Wave Infrared Pulses.

ACS photonics·2026
Same author

Pulsed Laser-Assisted Phase Engineering of Multimetallic Colloidal Nanocrystals With Complex Compositions.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Chirality Transfer via Orientational Order of Micellar Assemblies on Gold Nanocrystals.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Engineering low-symmetry colloidal crystals with optical anisotropies.

Science advances·2026
Same author

Decellularized Dermis ECM-Based Melanoma-on-a-Chip Model with Integrated Lymphatic and Vascular Networks for High-Throughput Drug Testing.

ACS applied bio materials·2026

Related Experiment Video

Updated: Jun 16, 2026

Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test
05:25

Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test

Published on: July 14, 2023

SERS-based diagnosis and biodetection.

Ramón A Alvarez-Puebla1, Luis M Liz-Marzán

  • 1Departamento de Quimica-Fisica and Unidad Asociada CSIC-Universidade de Vigo 36310 Vigo, Spain. ramon.alvarez@uvigo.es

Small (Weinheim an Der Bergstrasse, Germany)
|January 29, 2010
PubMed
Summary
This summary is machine-generated.

Surface-enhanced Raman scattering (SERS) spectroscopy offers powerful molecular identification and single-molecule detection. This review discusses SERS advances and limitations for biodetection and disease diagnosis using encoded nanoparticles.

More Related Videos

Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics
07:17

Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics

Published on: March 13, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Related Experiment Videos

Last Updated: Jun 16, 2026

Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test
05:25

Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test

Published on: July 14, 2023

Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics
07:17

Exploring the Application of Surface-enhanced Raman Scattering-based Biosensing of Individual sEVs in Disease Diagnosis and Therapeutics

Published on: March 13, 2026

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Nanotechnology

Background:

  • Surface-enhanced Raman scattering (SERS) is a highly sensitive technique for molecular identification.
  • SERS has the potential for single-molecule detection under ambient conditions.
  • SERS applications are expanding in biodetection and medical diagnostics.

Purpose of the Study:

  • To provide an overview of recent advances in SERS for diagnosis and biodetection.
  • To discuss the limitations of SERS in these applications.
  • To highlight the use of SERS with encoded nanoparticles for ultradetection and disease diagnosis.

Main Methods:

  • Review of current literature on SERS applications.
  • Discussion of SERS principles and advancements.
  • Focus on encoded nanoparticles for enhanced biodetection.

Main Results:

  • SERS enables ultradetection of bioanalytes and rapid disease diagnosis.
  • Encoded nanoparticles improve SERS sensitivity and specificity.
  • SERS facilitates cellular organelle marking and non-invasive tissue tagging.

Conclusions:

  • SERS is a promising technique for sensitive biodetection and medical diagnostics.
  • Further research is needed to overcome SERS limitations.
  • Encoded nanoparticles represent a key development for advanced SERS applications.