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Updated: Jun 16, 2026
Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 27, 2010
[Env gene sequencing and HIV-1 subtyping of infected MSM from Beijing]
Hong-Hai Zhang1, Yu Sun, Ya-Li Liu
1STD & HIV/AIDS Research Laboratory, You' An Hosipital, affiliated to Capital Medical University, Beijing 100069, China.
Objective:
To comprehend the latest HIV-I epidemic tendency and the character of V3 loop in MSM population of Beijing. METHODS; The C2-V3 regions of the HIV envelop gene were amplified by nest-PCR and sequenced from 11 HIV-l-infected MSM in Beijing in 2007. The subtype and sequences of V3 loop was analyzed. RESULTS There are 4 subtype B strains, 5 CRF AE, 1 CRFO7BC and 1 CRF15-01B strains within all 11 strains. There are five types of central motifs of the 11 samples, in which GPGR and GPGQ are most common.
Conclusion:
Recombination subtype of HIV-1 are spread extensively in MSM population of Beijing.
