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Insulin-sensitivity response to a single bout of resistive exercise in type 1 diabetes mellitus
Carolyn Jimenez1, Mayra Santiago, Michael Sitler
1Dept of Sports Medicine, West Chester University, West Chester, PA, USA.
Context:
Little is known about the acute effects of resistance exercise on insulin sensitivity in people with type 1 diabetes.
Design:
Repeated-measures design with 2 independent variables: group (exercise and nonexercise control) and time (preexercise and 12 and 36 h postexercise).
Setting:
General Clinical Research Center, Temple University Hospital, Philadelphia, PA.
Patients:
14 physically active subjects (11 men and 3 women) with type 1 diabetes.
Intervention:
The exercise group completed 5 sets of 6 repetitions of strenuous (80% 1-RM) quadriceps and hamstring exercises while the control group performed only activities of daily living.
Main Outcome Measures:
Insulin sensitivity was assessed with the euglycemic-hyperinsulinemic-clamp technique preexercise and 12 and 36 h postexercise.
Results:
Insulin-sensitivity values were not significantly different between the exercise and control groups (P = .92) or over time (P = .67).
Conclusions:
A single bout of strenuous resistance exercise does not alter insulin sensitivity in people with type 1 diabetes.
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