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VIGS-Mediated Forward Genetics Screening for Identification of Genes Involved in Nonhost Resistance

VIGS-Mediated Forward Genetics Screening for Identification of Genes Involved in Nonhost Resistance

Published on: August 23, 2013

Genetically engineered virus-resistant plants in developing countries: current status and future prospects.

D V R Reddy¹, M R Sudarshana, M Fuchs

¹Venkata Villa, Hyderabad, 500034, India.

Advances in Virus Research

|January 30, 2010

Summary

This summary is machine-generated.

Developing genetically engineered virus-resistant (GEVR) crops is crucial for global food security. Overcoming socio-economic and regulatory hurdles is key to deploying these advanced plant technologies, especially in developing nations.

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Area of Science:

Agricultural Science
Plant Pathology
Biotechnology

Background:

Plant viruses cause significant global crop losses, with conventional control methods showing limited efficacy.
Developing virus-resistant (VR) plants, particularly through genetic engineering, offers a promising solution to mitigate these impacts.
While numerous strategies exist, few genetically engineered virus-resistant (GEVR) crops have reached commercialization, especially in developing countries.

Purpose of the Study:

To review current strategies for engineering virus resistance in plants, focusing on both viral and non-viral gene applications.
To identify the socio-economic and regulatory challenges hindering the adoption of GEVR crops in developing countries.
To propose solutions for overcoming these barriers and facilitating the deployment of GEVR crops.

Main Methods:

Exploitation of natural resistance sources through conventional breeding.
Genetic engineering of plants using viral-derived genes (e.g., coat protein, replicase) and non-viral genes (e.g., R genes, microRNAs).
Analysis of socio-economic factors, intellectual property rights, biosafety regulations, and public perception impacting GEVR crop adoption.

Main Results:

Both viral and non-viral genes have been successfully employed to engineer virus resistance in plants.
Significant interest exists in developing countries for GEVR crops, despite limited availability.
Key barriers include socio-economic issues, intellectual property, biosafety frameworks, costs, and activist opposition.

Conclusions:

Genetic engineering offers potent tools for developing virus-resistant crops, complementing conventional breeding.
Addressing socio-economic and regulatory challenges is paramount for the successful introduction of GEVR crops in developing nations.
Collaborative efforts are needed to navigate challenges and realize the potential of GEVR crops for global food security.