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Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...

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Related Experiment Video

Updated: Jun 16, 2026

Apparatus for Harvesting Tissue Microcolumns
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Published on: October 25, 2018

[What's new in dermatological research?].

O Dereure1

  • 1Service de dermatologie, Hôpital Saint-Eloi, Montpellier, France. o-dereure@chu-montpellier.fr

Annales De Dermatologie Et De Venereologie
|January 30, 2010
PubMed
Summary

Dermatology research advanced in 2023, focusing on inflammatory diseases, psoriasis, and genetic skin conditions. International studies and computational methods are deepening our molecular understanding of skin disorders.

Area of Science:

  • Immunodermatology
  • Genetics of skin diseases
  • Computational biology in dermatology

Context:

  • Recent advancements in fundamental dermatology research.
  • Growing focus on the immunological basis of skin conditions.
  • Increasing prominence of in silico investigations and international collaborations.

Purpose:

  • To review key developments in dermatology research over the past year.
  • To highlight progress in understanding inflammatory diseases, genetic disorders, and skin cancers.
  • To emphasize the role of computational approaches and global research efforts.

Summary:

  • Research has actively explored the immunological underpinnings of inflammatory skin diseases.
  • Identification of genetic risk loci for psoriasis, tumors, and cutaneous lymphomas has advanced.

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Apparatus for Harvesting Tissue Microcolumns
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A Rat Model of Compound Acne
03:10

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Published on: November 1, 2024

  • International collaborative studies have improved the molecular understanding of genodermatoses, particularly those affecting pigmentation and differentiation.
  • In silico investigations are becoming increasingly significant, influenced by China's growing research capacity.

    • Impact:

    • Enhanced molecular understanding of various dermatological conditions.
    • Potential for future practical interventions in skin disease treatment.
    • Growing integration of computational methods in dermatological research and discovery.