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A Multiplex Serological Assay for the Detection of Antibody Responses to Arboviruses
Published on: November 4, 2025
[Methodology and applicability of seroepidemiological surveys]
1Direcció General de Salut Pública, Departament de Salut, Generalitat de Catalunya, España. pedro.plans@gencat.cat
Abstract:
Seroepidemiological surveys can be defined as seroepidemiological studies carried out in population samples to investigate immunity levels against vaccinable and not vaccinable diseases. The objective of this paper is to present the methodology and applicability of serological surveys. Problems related to seroepidemiological surveys in immigrant population are also discussed. Seroepideniological surveys should be developed in representative samples of the population, determining the sample size taking into account the sample error and precision that should be obtained for population parameters. It is necessary to develop an adequate questionnaire to collect sociodemographical and medical information from all participants. Serological tests should sensitive and specific. Seroepidemiological surveys can be used assess immunity levels in different population groups, and to detect sociodemographical and medical variables associated with the immunity, vaccination and infectious diseases.
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