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Liver-metastatic human colon carcinoma in immunosuppressed mice
11st Institute of Pathology, Semmelweis Medical University, Budapest, Hungary.
Neoplasma
|January 1, 1991
Abstract:
An experimental liver metastasis model using the HT-29 human colon carcinoma cell line is described. The tumor xenograft in immunosuppressed mice preserved the histological type as well as the human and gastrointestinal markers (HLA-I, CEA). This model seems to be suitable for the development of new therapeutic protocols as well as for the study of metastasizing of a frequent human tumor type.