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Updated: Jun 16, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Accuracy of computed tomography attenuation measurements for diagnosing anemia
Hai Lan1, Sadamitsu Nishihara, Hiromu Nishitani
1Department of Radiology, Graduate School of Medical Sciences, The University of Tokushima, Tokushima, Japan.
Purpose:
The purpose of this study was to determine which computed tomography (CT) attenuation parameter was the most appropriate to predict the presence or severity of anemia.
Materials And Methods:
The subjects of the study wer 500 patients who had undergone a peripheral blood examination within 24 h of an unenhanced CT scan. Regions of interest were placed in the left ventricular (LV) cavity, thoracic and abdominal aortic lumens, inferior vena cava, and interventricular septum. The CT attenuation difference between the LV cavity and interventricular septum was also calculated. The relation between these measurements and the blood hemoglobin level was analyzed. In addition, using several selected parameters, a receiver operating characteristic (ROC) analysis was also performed.
Results:
The difference in CT attenuation between the LV cavity and interventricular septum revealed the greatest correlation. ROC analyses also revealed the greatest area under the ROC curve in the differences between CT attenuation.
Conclusion:
The best quantitative method for the diagnosis of anemia was the difference in CT attenuation between the left ventricle and interventricular septum.
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