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Updated: Jun 16, 2026

In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse
Published on: October 25, 2024
Th17 cytokines and vaccine-induced immunity
Yinyao Lin1, Samantha R Slight, Shabaana A Khader
1Department of Pediatrics and Immunology, University of Pittsburgh School of Medicine, PA, 15224, USA.
None:
T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in primary immune responses against infections is well documented, there is growing evidence that the Th17 lineage maybe critical for vaccine-induced memory immune responses against infectious diseases. Here, we summarize recent progress in our understanding of the role of IL-17 in vaccine-induced immunity.
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