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Updated: Jun 16, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
[Severe ovarian hyperstimulation syndrome after exogenous administration of human chorionic gonadotropin]
O Aznar Millán1, R Ramos Aparici, J Campos Pérez
1Servicio Anestesiología, Reanimación y Tratamiento del Dolor, Hospital General de Castellón, Castellón de la Plana. dra_olga@hotmail.com
Abstract:
Severe ovarian hyperstimulation syndrome can occur after administration of human chorionic gonadotropin used to induce ovulation in the context of in-vitro fertilization protocols. We report the case of a 27-year-old woman who had received gonadotropin treatment. In-vitro fertilization was successful but she developed abdominal pain, ascites, lower limb edema, dyspnea, bilateral pleural effusion, and adult respiratory distress syndrome. The patient was admitted to the intensive care unit, where mechanical ventilation was started. Uterine dilatation and curettage was required to halt the process.
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