Surgical conditions of the diaphragm: posterior diaphragmatic hernias in infants
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Published on: February 5, 2021
Priscilla P L Chiu1, Jacob C Langer
1Division of Pediatric General and Thoracic Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada.
Insights
Care for neonates with congenital diaphragmatic hernia (CDH) has advanced, improving survival rates. However, long-term health issues are now more recognized, with ongoing debates in treatment strategies.
Area of Science:
- Neonatal care
- Pediatric surgery
- Congenital anomalies
Background:
- Congenital diaphragmatic hernia (CDH) management has shifted from aggressive ventilation and emergency surgery.
- Current approaches emphasize permissive hypercapnia, stabilization, elective repair, and multidisciplinary follow-up.
Purpose of the Study:
- To outline the evolution of CDH care.
- To highlight survival improvements and associated morbidities.
- To identify areas of ongoing controversy in CDH management.
Main Methods:
- Review of evolving clinical practices in CDH care.
- Analysis of survival rates and associated morbidities.
- Discussion of controversial management topics.
Main Results:
- Overall survival for neonates with CDH now approaches 80%.
- Improved survival is linked to increased recognition of respiratory, cardiac, gastrointestinal, and neurodevelopmental morbidities.
Conclusions:
- Neonatal care for CDH has significantly improved survival.
- Long-term morbidities require continued attention and research.
- Key areas of controversy include fetal tracheal occlusion, ECMO, and minimally invasive surgical techniques.
Abstract:
The care of the neonate with CDH has significantly evolved from an approach characterized by aggressive ventilation and emergency surgical repair, to the current use of permissive hypercapnea, physiologic stabilization, elective surgical repair, and multidisciplinary follow-up. Overall survival now approaches 80%, but this improvement has been associated with increased recognition of respiratory, cardiac, gastrointestinal, and neurodevelopmental morbidity. Topics of continuing controversy in the management of CDH include the value of fetal tracheal occlusion, the expanding role of ECMO, and the use of minimal access techniques for surgical repair.
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