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Related Concept Videos

Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

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Allergies in India: an analysis of 3389 patients attending an allergy clinic in Mumbai, India.

Journal of the Indian Medical Association·2008
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Skin prick test--more reliable than estimation of specific IgE in allergy diagnosis.

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Related Experiment Video

Updated: Jun 16, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

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Allergies in India: a study on medication compliance.

Wiqar A Shaikh1, Shifa Wiqar Shaikh

  • 1Allergy and Asthma Clinic, Mumbai 400007.

Journal of the Indian Medical Association
|February 2, 2010
PubMed
Summary

This study found surprisingly low medication adherence among young Indian patients with allergic diseases. Sublingual immunotherapy showed the highest compliance, while nasal sprays had the lowest.

Area of Science:

  • Allergy and Immunology
  • Pharmacology
  • Public Health

Background:

  • Limited research exists on medication compliance for allergic diseases in India.
  • Allergic conditions like asthma, rhinitis, and urticaria require consistent treatment adherence.
  • Understanding compliance is crucial for effective disease management and patient outcomes.

Purpose of the Study:

  • To investigate and quantify medication compliance rates for various allergic disease treatments in Indian patients.
  • To identify variations in compliance across different medication classes, including nasal sprays, inhalers, immunotherapy, and antihistamines.

Main Methods:

  • A prospective study involving 80 young patients (10-40 years) with asthma and rhinitis or urticaria.
  • Medication compliance was monitored over one year using detailed dose diaries.

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

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Published on: March 3, 2023

  • Data collected from patients attending a private clinic.
  • Main Results:

    • Overall medication compliance rates were found to be lower than anticipated.
    • Sublingual immunotherapy demonstrated the highest compliance at 84.19%.
    • Nasal spray compliance was the lowest at 62.32%, followed by dry powder inhalers (69.31%) and fexofenadine tablets (71.78%).

    Conclusions:

    • There is a significant need to improve medication adherence for allergic diseases in India.
    • Targeted interventions may be required to enhance compliance, particularly for nasal sprays and inhalers.
    • The low compliance rates observed in a private clinic setting warrant further investigation into underlying factors.