Venous thromboembolism in children

Neil A Goldenberg1, Timothy J Bernard

  • 1Mountain States Regional Hemophilia and Thrombosis Center, Aurora, CO 80045-0507, USA.

Insights

Pediatric venous thromboembolism (VTE) is a growing concern due to increased survival rates and invasive procedures. This review covers VTE causes, diagnosis, and management in children.

Area of Science:

  • Pediatric Medicine
  • Hematology
  • Vascular Medicine

Background:

  • Improved survival in critically ill children increases risk for venous thromboembolism (VTE).
  • Increased use of invasive vascular devices contributes to pediatric VTE.
  • Vascular events are increasingly recognized in the pediatric population.

Purpose of the Study:

  • To provide a comprehensive overview of pediatric venous thromboembolism (VTE).
  • To discuss the etiology, epidemiology, clinical presentation, diagnosis, and management of pediatric VTE.
  • To highlight prognostic indicators, long-term outcomes, and areas for future research in pediatric VTE.

Main Methods:

  • Literature review focusing on etiology, epidemiology, and clinical aspects of pediatric VTE.
  • In-depth discussion of diagnostic evaluation and management strategies.
  • Consideration of prognostic factors and long-term outcomes based on existing evidence.

Main Results:

  • Venous thromboembolism (VTE) is a significant and increasing concern in pediatrics.
  • Understanding the background, clinical characterization, and diagnostic approaches is crucial for managing pediatric VTE.
  • Evidence-based management and further research are needed for optimal long-term outcomes.

Conclusions:

  • Pediatric venous thromboembolism (VTE) requires careful consideration due to rising incidence.
  • Effective management involves thorough clinical characterization and diagnostic evaluation.
  • Further research is essential to improve prognostic indicators and long-term outcomes for pediatric VTE.

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