Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metallomic Signatures of Lung Cancer and Chronic Obstructive Pulmonary Disease.

International journal of molecular sciences·2023
Same author

Eosinophil Subtypes in Adults with Asthma and Adults with Chronic Obstructive Pulmonary Disease.

American journal of respiratory and critical care medicine·2023
Same author

Somatotypes trajectories during adulthood and their association with COPD phenotypes.

ERJ open research·2020
Same author

A Delphi Consensus Document on the Use of Single-Inhaler Fixed-Dose Triple Therapies in COPD Patients.

International journal of chronic obstructive pulmonary disease·2020
Same author

Prognostic Validation Using GesEPOC 2017 Severity Criteria.

Archivos de bronconeumologia·2019
Same author

Determinants of the Appearance and Progression of Early-Onset Chronic Obstructive Pulmonary Disease in Young Adults. A Case-Control Study with Follow-up.

Archivos de bronconeumologia·2018
Same journal

Advances in Sarcoidosis.

Archivos de bronconeumologia·2026
Same journal

Spanish Clinical Practice Guidelines for the Diagnosis and Management of Alpha-1 Antitrypsin Deficiency: 2026 Update.

Archivos de bronconeumologia·2026
Same journal

Thoracic Sympathectomy for Harlequin Syndrome.

Archivos de bronconeumologia·2026
Same journal

Prognostic Significance of Electrocardiographic Findings in Hemodynamically Stable Patients With Acute Pulmonary Embolism: Insights From the RIETE Registry.

Archivos de bronconeumologia·2026
Same journal

Endothelial and Angiogenic Biomarkers in Obstructive Sleep Apnea: Longitudinal Associations With Continuous Positive Airway Pressure.

Archivos de bronconeumologia·2026
Same journal

Robotic Resection of Ectopic Paratracheal Thymoma: A Case Report.

Archivos de bronconeumologia·2026
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
08:44

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method

Published on: February 2, 2024

[COPD: what is there beyond BODE index?].

Ciro Casanova Macario1, Juan Pablo de Torres Tajes, Elizabeth Córdoba Lanus

  • 1Servicio de Neumología, Unidad de Investigación, Hospital Universitario La Candelaria, Santa Cruz de Tenerife, España. casanovaciro@gmail.com

Archivos De Bronconeumologia
|February 2, 2010
PubMed
Summary
This summary is machine-generated.

Chronic obstructive pulmonary disease (COPD) assessment needs more than FEV1. Evaluating multiple variables, including new technologies, can improve patient management for this common respiratory disease.

Related Experiment Videos

Last Updated: Jun 16, 2026

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
08:44

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method

Published on: February 2, 2024

Area of Science:

  • Pulmonology
  • Internal Medicine

Context:

  • Chronic obstructive pulmonary disease (COPD) exhibits significant phenotypic heterogeneity.
  • Current assessment methods, like FEV1, inadequately capture disease complexity.
  • Comprehensive patient evaluation requires integrating multiple clinical variables.

Purpose:

  • To highlight the limitations of FEV1 in COPD assessment.
  • To emphasize the need for multidimensional assessment tools.
  • To explore the potential of novel technologies in COPD evaluation.

Summary:

  • COPD is a complex disease not fully defined by FEV1.
  • The BODE index is a recognized multidimensional tool, but omits key factors like hyperinflation, exacerbations, and comorbidities.
  • Emerging technologies offer potential for improved disease characterization and personalized management.

Impact:

  • Current COPD assessment tools may not fully reflect disease severity or progression.
  • Integrating additional clinical variables and advanced technologies can enhance patient stratification.
  • Further research is needed to define the role of these factors in clinical practice for COPD.