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Related Concept Videos

Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
Inflammatory Bowel Disease V: Surgical Management01:21

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Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
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Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

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Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
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Related Experiment Video

Updated: Jun 16, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

[Large iatrogenic colonic perforation treated by endoscopic suturing].

J-F Demarquay1, H Perrin, P Hastier

  • 1Service d'Hépatogastro-Entérologie du Centre Hospitalier Princesse-Grace, Principauté de Monaco, avenue Pasteur, 98012 Monaco cedex, France. jean-francois.demarquay@chpg.mc

Gastroenterologie Clinique Et Biologique
|February 2, 2010
PubMed
Summary

Endoscopic suturing with hemoclips successfully treated two large colonic perforations (≥10mm), offering a minimally invasive alternative to surgery for this severe colonoscopy complication.

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Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Colorectal Surgery

Background:

  • Colonic perforation is a severe complication of colonoscopy, with surgery as the traditional treatment.
  • Interventional endoscopy, including endoscopic suturing, has emerged as a potential alternative.
  • Previous reports focused on smaller perforations (<10mm).

Observation:

  • This study reports on two cases of colonic perforations, both measuring at least 10mm.
  • The perforations occurred during diagnostic colonoscopy (sigmoid diverticulum) and endoscopic mucosal resection (ascending colon).
  • Both perforations were successfully treated using endoscopic suturing with hemoclips.

Findings:

  • Endoscopic hemoclip suturing is effective for managing larger colonic perforations (≥10mm).
  • This technique provides a minimally invasive treatment option, potentially avoiding surgery.
  • Successful closure was achieved in both reported cases, regardless of perforation etiology.

Implications:

  • Endoscopic suturing may expand the non-operative management options for colonic perforations.
  • This approach could reduce the need for surgical intervention, lowering patient morbidity.
  • Further research is warranted to establish the safety and efficacy of endoscopic suturing for larger perforations.