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Updated: Jun 16, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
[Large iatrogenic colonic perforation treated by endoscopic suturing].
J-F Demarquay1, H Perrin, P Hastier
1Service d'Hépatogastro-Entérologie du Centre Hospitalier Princesse-Grace, Principauté de Monaco, avenue Pasteur, 98012 Monaco cedex, France. jean-francois.demarquay@chpg.mc
Endoscopic suturing with hemoclips successfully treated two large colonic perforations (≥10mm), offering a minimally invasive alternative to surgery for this severe colonoscopy complication.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Colorectal Surgery
Background:
- Colonic perforation is a severe complication of colonoscopy, with surgery as the traditional treatment.
- Interventional endoscopy, including endoscopic suturing, has emerged as a potential alternative.
- Previous reports focused on smaller perforations (<10mm).
Observation:
- This study reports on two cases of colonic perforations, both measuring at least 10mm.
- The perforations occurred during diagnostic colonoscopy (sigmoid diverticulum) and endoscopic mucosal resection (ascending colon).
- Both perforations were successfully treated using endoscopic suturing with hemoclips.
Findings:
- Endoscopic hemoclip suturing is effective for managing larger colonic perforations (≥10mm).
- This technique provides a minimally invasive treatment option, potentially avoiding surgery.
- Successful closure was achieved in both reported cases, regardless of perforation etiology.
Implications:
- Endoscopic suturing may expand the non-operative management options for colonic perforations.
- This approach could reduce the need for surgical intervention, lowering patient morbidity.
- Further research is warranted to establish the safety and efficacy of endoscopic suturing for larger perforations.
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