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Updated: Jun 16, 2026

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
New insights to primary photodynamic effects--Singlet oxygen kinetics in living cells
Steffen Hackbarth1, Jan Schlothauer, Annegret Preuss
1Humboldt-Universität zu Berlin, Institute of Physics, Photobiophysics, Newtonstr. 15, 12489 Berlin, Germany. hacky@physik.hu-berlin.de
Abstract:
The kinetics of chemical singlet oxygen quencher consumption inside living cells during low dose illumination was revealed via time resolved singlet oxygen luminescence detection. Deviations of the measured data from the common theoretical model for (1)O(2) kinetics forced the authors to consider a one-dimensional diffusion model for description of the kinetics of singlet oxygen generated by membrane localized photosensitizers. Our observations reconcile seemingly contradictory reports presenting different values for the efficiency of singlet oxygen interaction with cells.

