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Effectiveness and acceptability of three bowel cleansing regimens
B Børkje1, R Pedersen, G M Lund
1Medical Dept., Haukeland University Hospital, Bergen, Norway.
Scandinavian Journal of Gastroenterology
|February 1, 1991
Summary
Three colon cleansing regimens showed similar patient acceptance and convenience for colonoscopy preparation. No regimen was clinically superior, though one polyethylene glycol solution offered a cleaner colon in outpatients.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
- Clinical Trials
Background:
- Effective colon cleansing is crucial for successful colonoscopy.
- Patient tolerance and preparation completeness vary among different bowel preparation regimens.
Purpose of the Study:
- To compare the effectiveness and acceptability of three distinct colon cleansing regimens for colonoscopy.
- To evaluate patient satisfaction and colon cleanliness across different preparation methods.
Main Methods:
- A prospective study involving 271 patients (in- and outpatients) randomly assigned to three regimens: X-prep, Golytely, or PicoSalax/Golytely combination.
- Patient-reported outcomes (palatability, convenience) and colonoscopist-assessed preparation completeness were measured using visual analogue scales.
Main Results:
- No significant differences in patient-reported palatability or convenience were observed between the three regimens.
- Regimen II (Golytely) resulted in a significantly cleaner colon in outpatients compared to regimen I (X-prep).
- Overall inadequate preparation rates were 14% (X-prep), 8% (Golytely), and 12% (PicoSalax/Golytely); outpatients had significantly cleaner colons than inpatients.
Conclusions:
- No clinically significant differences were found among the three bowel preparation regimens in terms of overall effectiveness and acceptability.
- Oral irrigation regimens are acceptable to patients and may offer greater flexibility in endoscopic settings.