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Updated: Jun 16, 2026

Perspectives on Neuroscience
26:41

Perspectives on Neuroscience

Published on: July 31, 2007

The adaptive brain: a neurophysiological perspective.

Teija Kujala1, Risto Näätänen

  • 1Cognitive Brain Research Unit, Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland. teija.m.kujala@helsinki.fi

Progress in Neurobiology
|February 2, 2010
PubMed
Summary
This summary is machine-generated.

Brain plasticity, crucial for learning and recovery, can be studied in humans using non-invasive evoked neural responses like mismatch negativity (MMN) and N1, even in non-communicative individuals.

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Published on: October 29, 2018

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neuroplasticity

Background:

  • Brain plasticity underlies skill acquisition, recovery from brain damage, and interventions.
  • Studying human brain plasticity is challenging due to limitations on invasive research methods.
  • Animal models do not fully capture higher cognitive functions like language and music.

Purpose of the Study:

  • To explore non-invasive methods for assessing human brain plasticity.
  • To investigate the utility of evoked neural responses for studying brain changes.
  • To determine if higher-order neural responses can track plasticity in challenging populations.

Main Methods:

  • Recording evoked neural responses, specifically mismatch negativity (MMN) and N1.
  • Utilizing methods applicable even in the absence of attention.
  • Applying techniques to individuals unable to communicate and infants.

Main Results:

  • Evoked neural responses provide insights into learning and recovery mechanisms.
  • Higher-order neural responses like MMN and N1 are recordable without attention.
  • These responses allow for the assessment of plastic neural changes in diverse human groups.

Conclusions:

  • Evoked neural responses offer a viable pathway to study human brain plasticity.
  • MMN and N1 are valuable tools for assessing neuroplasticity in non-communicative patients and infants.
  • This approach overcomes limitations of invasive methods and animal models for higher cognitive functions.