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Updated: Jun 16, 2026

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
Published on: December 15, 2017
Wireless capsule in inflammatory bowel disease
M Flamant1, C Trang, A Bourreille
1Institut des Maladies de l'Appareil Digestif, CHU Hôtel-Dieu, Nantes, France.
Abstract:
Capsule endoscopy (CE) is a safe, non-invasive diagnostic tool to evaluate small bowel lesions. CE, like conventional endoscopy, can detect focal and small-ulcerated lesions along the entire length of the small bowel, which are not identified by other imaging techniques. Meta-analysis has shown that CE is better than any other radiological technique to detect small bowel lesions in patients with suspected or known Crohn's disease (CD). In unclassified colitis, CE is also useful in distinguishing CD and ulcerative colitis (UC). In established CD, CE may be used to detect post-operative recurrence, determine the extent of small bowel lesions and link ulcerated lesions with clinical symptoms. Although CE is well tolerated there is a theoretical risk of capsule impaction in general and in CD in particular. To avoid capsule impaction, a new option called the "patency capsule" is available especially in patients with symptoms suggesting small bowel obstruction. However, few data are available about this new device and its use in clinical practice needs to be clarified.
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