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Updated: Jun 16, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Contrast guided two-dimensional echocardiography for needle localization during pericardiocentesis: a case report
Jeffrey M Schussler1, Paul A Grayburn
1Department of Internal Medicine, Division of Cardiology, Baylor University Medical Center, Dallas, Texas 75226, USA. jschussler@heartplace.com
Agitated saline safely guided pericardiocentesis needle placement for pericardial effusion drainage. This method confirmed needle position, preventing catheter misplacement into the right ventricle.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Procedures
Background:
- Pericardial effusion diagnosis and management.
- Challenges in pericardiocentesis needle placement.
- Echocardiography as a guidance tool.
Observation:
- A case of pericardial effusion requiring drainage.
- Utilized agitated saline as an echocardiographic contrast agent.
- Visualized needle tip within the pericardial space.
Findings:
- Agitated saline effectively confirmed pericardiocentesis needle location.
- The technique ensured accurate needle placement before catheter insertion.
- Prevented inadvertent catheter placement into the right ventricle.
Implications:
- Agitated saline offers a safe and reliable method for echocardiographic contrast in pericardiocentesis.
- Enhances procedural safety and efficacy in draining pericardial effusions.
- Potential to reduce complications associated with pericardiocentesis.
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