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Related Experiment Video

Updated: Jun 16, 2026

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency

Published on: September 15, 2021

[Cellular localization and tissue expression pattern of UCA1, a non-coding RNA].

Xiao-juan Xie¹, Xu Li, Fan Wang

¹Center for Molecular Medicine, First Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710061, China. xie198105@163.com

Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University

|February 2, 2010

Summary

This summary is machine-generated.

Urothelial carcinoma-associated 1 (UCA1) is found in the cytoplasm and its expression correlates with bladder cancer progression, suggesting it may serve as a specific bladder cancer marker.

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Area of Science:

Molecular biology
Genetics
Oncology

Context:

Urothelial carcinoma-associated 1 (UCA1) is a long non-coding RNA.
The role of UCA1 in bladder carcinoma is not fully understood.

Purpose:

To determine the subcellular localization of UCA1.
To analyze the tissue expression of UCA1.
To investigate the association between UCA1 expression and bladder cancer progression.

Summary:

UCA1 was found in the cell membrane, cytoplasm, and nuclei.
UCA1 is overexpressed in placental and fetal bladder tissues.
UCA1 expression is elevated in various tumor tissues, notably in bladder cancer compared to normal bladder tissues.

Impact:

UCA1 is located in the cytoplasm.
UCA1 expression levels correlate with bladder cancer progression.
UCA1 shows potential as a specific biomarker for bladder cancer detection and management.