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Updated: Jun 16, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Experience with a pill-swallowing enhancement aid.
Shelley Diamond1, Danielle C Lavallee
1Pedipharm Consultants, Toronto, ON, Canada.
Pill Glide, a new flavored spray, helped 7 out of 11 adolescents overcome difficulty swallowing pills. This study shows promise for improving medication adherence in young people with swallowing challenges.
Area of Science:
- Pediatric medicine
- Pharmacology
- Swallowing disorders
Background:
- Difficulty swallowing tablets and capsules (dysphagia) is a significant barrier to medication adherence in adolescents.
- Limited tools exist to aid pediatric patients experiencing challenges with oral medication administration.
- Adolescent self-report identified past difficulties with swallowing solid oral dosage forms.
Purpose of the Study:
- To assess the efficacy of Pill Glide, a flavored oral spray, in facilitating tablet and capsule swallowing among adolescents.
- To evaluate Pill Glide's potential to improve medication adherence in pediatric populations.
- To provide initial findings on a novel intervention for pediatric dysphagia.
Main Methods:
- A convenience sample of 11 adolescents (ages 9-17) with self-reported past swallowing difficulties participated.
- Participants used Pill Glide spray, a flavored agent designed to aid swallowing.
- A tic tac candy was used to simulate medication intake; success/failure of swallowing was recorded with water.
Main Results:
- Seven out of eleven (63.6%) adolescent participants successfully swallowed the simulated medication (tic tac) using Pill Glide.
- The intervention demonstrated a positive outcome in a majority of participants with reported swallowing issues.
- Initial findings indicate Pill Glide's potential to assist adolescents with oral medication intake.
Conclusions:
- Pill Glide spray shows promise as an effective aid for adolescents experiencing difficulty swallowing medications.
- This intervention may improve medication adherence rates in pediatric populations with dysphagia.
- Further research is warranted to confirm Pill Glide's utility in real-world medication regimens.
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