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Updated: Jun 16, 2026

Lensless Fluorescent Microscopy on a Chip
Published on: August 17, 2011
Data compression and enhancement of sampled images
Abstract:
A two-dimensional sampled image can be represented by an equal number of spatial frequencies in the Fourier domain. However, due to physical limitations of the sampling process, there exists an effective cutoff frequency beyond which no information is preserved. The knowledge of this cutoff frequency is very important, since a considerable amount of additional noise can be introduced by frequency components above this cutoff. Availability of a sharp edge within the image allows, within the linear theory, the estimation of the transfer function of the digitizing process itself. This calculated transfer function may be used for image enhancement below the cutoff frequency. In addition, significant amount of data compression may be achieved by removing all spatial frequency terms above the cutoff frequency. An example of this technique is developed utilizing a tribar resolution chart sampled at 1024 x 1024 points.
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