Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Psychophysiological response patterns in panic disorder.

R Hoehn-Saric1, D R McLeod, W D Zimmerli

  • 1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Acta Psychiatrica Scandinavica
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mapping of SPECT regional cerebral perfusion abnormalities in obsessive-compulsive disorder.

Human brain mapping·2014
Same author

Dental abnormalities in Schimke immuno-osseous dysplasia.

Journal of dental research·2012
Same author

A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2009
Same author

Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2008
Same author

Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics·2008
Same author

Rare plus common SERT variants in obsessive-compulsive disorder.

Molecular psychiatry·2007

Patients with panic disorder show heightened physiological arousal, including increased cardiovascular activity and reduced electrodermal flexibility, even at rest or during mild stress. This suggests underlying hyperarousal in panic disorder.

Area of Science:

  • Psychophysiology
  • Clinical Psychology
  • Anxiety Disorders

Background:

  • Panic disorder is characterized by recurrent, unexpected panic attacks.
  • Physiological hyperarousal is often implicated in the pathophysiology of panic disorder.
  • Previous research has yielded mixed findings regarding physiological differences between panic disorder patients and controls.

Purpose of the Study:

  • To investigate physiological differences between panic disorder patients and nonanxious controls during rest and mild psychological stress.
  • To determine if panic disorder patients exhibit hyperarousal in non-panic-inducing situations.

Main Methods:

  • Compared 18 panic disorder patients with frequent panic attacks to nonanxious controls.
  • Utilized a battery of physiological assessments, including forehead electromyographic activity, systolic blood pressure, heart rate, and skin conductance response.

Related Experiment Videos

  • Administered mild psychological stress during assessments.

    • Main Results:

    • Panic disorder patients exhibited higher baseline forehead electromyographic activity, systolic blood pressure, and heart rates compared to controls.
    • During stress, panic disorder patients showed greater increases in heart rate and systolic blood pressure.
    • Nonanxious controls displayed greater and more variable skin conductance responses.

    Conclusions:

    • Panic disorder patients with frequent panic attacks demonstrate heightened cardiovascular arousal and reduced electrodermal flexibility, even in non-threatening contexts.
    • These findings suggest a persistent state of physiological hyperarousal in panic disorder.
    • The results contribute to understanding the psychophysiological underpinnings of panic disorder.