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Updated: Jun 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

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Malignant struma ovarii: a case report.

Gülseren Yücesoy¹, Yigit Cakiroglu, Bahar Muezzinoglu

¹Department of Obstetrics and Gynecology, Kocaeli University, School of Medicine, Kocaeli, Turkey. gulserene@superonline.com

Journal of Korean Medical Science

|February 2, 2010

Summary

This case study details a primary malignant struma ovarii in a 40-year-old woman. Surgical management and monitoring achieved an 18-month disease-free outcome.

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Area of Science:

Gynecologic Oncology
Endocrinology

Background:

Malignant struma ovarii (MSO) is a rare ovarian teratoma containing thyroid tissue with malignant potential.
Primary MSO, originating in the ovary, is exceptionally uncommon, posing diagnostic and therapeutic challenges.

Observation:

A 40-year-old woman presented with pelvic pain and a palpable pelvic mass.
Initial investigations including tumor markers and biochemistry were unremarkable.
Gynecological examination revealed a large pelvic mass.

Findings:

Post-operative histopathology confirmed primary malignant struma ovarii.
The patient underwent total abdominal hysterectomy and bilateral salpingo-oopherectomy, followed by retroperitoneal pelvic lymphadenectomy for staging.
Despite normal findings in the left ovary and lymph nodes, thyroidectomy was declined by the patient.

Keywords:

Struma Ovarii Thyroglobulin Whole Body Imaging

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Last Updated: Jun 16, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Implications:

This case highlights the importance of histopathological evaluation for diagnosing rare ovarian malignancies.
Management requires a multidisciplinary approach, considering surgical staging and potential adjuvant therapies.
Long-term surveillance, including thyroglobulin monitoring, is crucial for detecting recurrence in malignant struma ovarii.