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Related Concept Videos

Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Portal Hypertension01:22

Portal Hypertension

Portal hypertension is an increase in blood pressure within the portal venous system. Normally, this pressure is less than 5 mmHg. It is considered clinically significant when it rises above 10 mmHg. At this threshold, complications from altered blood flow and venous congestion emerge.EtiologyPortal hypertension arises from conditions that impede blood flow through the liver. The most common cause is cirrhosis, in which chronic liver injury leads to fibrotic scarring. This fibrosis narrows or...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...

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Related Experiment Video

Updated: Jun 16, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
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Published on: August 8, 2025

Massive hepatic cyst presenting as right-sided heart failure.

A O'Connor1, M Lee, G McEntee

  • 1Department of Surgery, Beaumont Hospital, Dublin 9, Ireland. aoconnor@rcsi.ie

Irish Journal of Medical Science
|February 2, 2010
PubMed
Summary

A large hepatic cyst caused right heart failure in a 70-year-old woman by compressing the right atrium. Surgical removal of the cyst resolved symptoms, highlighting this rare cause of cardiac dysfunction.

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Area of Science:

  • Hepatology
  • Cardiology
  • Radiology

Background:

  • Right heart failure is typically associated with cardiac or pulmonary pathology.
  • Hepatic masses can rarely cause cardiac compromise through external compression.

Observation:

  • A 70-year-old woman presented with symptoms of right heart failure.
  • Echocardiogram revealed a hepatic cyst affecting venous return and right atrial filling.
  • CT abdomen confirmed a large cystic mass in the right hepatic lobe compressing the right atrium.

Findings:

  • Initial percutaneous drainage provided temporary symptom relief.
  • Recurrence of symptoms occurred due to fluid re-accumulation in the cyst.
  • Definitive treatment via cyst excision resulted in complete symptomatic cure.

Implications:

  • This case represents the first reported instance of a hepatic cyst causing right heart failure via right atrial compression.
  • Highlights the importance of considering non-cardiac masses in the differential diagnosis of right heart failure.
  • Emphasizes the role of advanced imaging and interventional procedures in managing rare hepatic pathologies with systemic effects.