Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Engineering Biomaterial-Drug Conjugates for Local and Sustained Chemotherapeutic Delivery.

Bioconjugate chemistry·2015

Same author

A bioreactor system for in vitro tendon differentiation and tendon tissue engineering.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2015

Same author

A silk-based encapsulation platform for pancreatic islet transplantation improves islet function in vivo.

Journal of tissue engineering and regenerative medicine·2015

Same author

Silk hydrogels for sustained ocular delivery of anti-vascular endothelial growth factor (anti-VEGF) therapeutics.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V·2015

Same author

Silk macromolecules with amino acid-poly(ethylene glycol) grafts for controlling layer-by-layer encapsulation and aggregation of recombinant bacterial cells.

ACS nano·2015

Same author

Biomineralization of stable and monodisperse vaterite microspheres using silk nanoparticles.

ACS applied materials & interfaces·2015

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

Electrospun silk material systems for wound healing.

Scott E Wharram¹, Xiaohui Zhang, David L Kaplan

¹Biomedical Engineering and Biotechnology, University of Massachusetts at Lowell, 1 University Avenue, Lowell, MA 01854, USA.

Macromolecular Bioscience

|February 2, 2010

Summary

Electrospun silk materials show promise as wound dressings, exhibiting suitable properties for healing. Silk concentration influences structural characteristics crucial for effective wound care systems.

More Related Videos

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers

Published on: September 4, 2017

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Published on: October 31, 2017

Related Experiment Videos

Last Updated: Jun 16, 2026

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Postproduction Processing of Electrospun Fibres for Tissue Engineering

Published on: August 9, 2012

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers

Microfluidic Dry-spinning and Characterization of Regenerated Silk Fibroin Fibers

Published on: September 4, 2017

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Fabrication and Characterization of Griffithsin-modified Fiber Scaffolds for Prevention of Sexually Transmitted Infections

Published on: October 31, 2017

Area of Science:

Biomaterials Science
Tissue Engineering
Wound Healing Research

Background:

Advanced wound dressings are critical for effective tissue regeneration.
Electrospun silk materials offer unique structural and biological properties.
Understanding silk material characteristics is key to developing optimal wound care solutions.

Purpose of the Study:

To evaluate the functional and biocompatible properties of electrospun silk materials.
To assess their suitability for full-thickness wound dressing applications.
To determine the influence of silk concentration on material properties.

Main Methods:

Evaluation of six distinct electrospun silk material groups.
Assessment of hydrated properties: absorption, water vapor transmission, oxygen permeation, and enzymatic biodegradation.
Application of constrained drying techniques to analyze structural influences.

Main Results:

All six silk matrices demonstrated suitable hydrated properties for wound healing.
Silk concentration was identified as a key factor in material structural properties.
Three electrospun silk models exhibited ideal biomaterial characteristics for wound dressings.

Conclusions:

Electrospun silk materials possess favorable properties for wound dressing applications.
Material structural properties, influenced by silk concentration, are critical for wound dressing systems.
Selected electrospun silk formulations show significant potential for clinical use in wound management.