Related Experiment Video
Updated: Jun 16, 2026

Pharmacophore Modeling for Targets with Extensive Ligand Libraries: A Case Study on SARS-CoV-2 Mpro
Published on: September 26, 2025
Modified problem-based learning in pharmacology
R Hudec1, J Tisonova, L Bozekova
1Department of Pharmacology and Clinical Pharmacology, Faculty ofMedicine, Comenius University, Bratislava, Slovakia. dr.hudec@gmail.com
Objective:
The aim of this study was to determine differences between PBL as compared to modified PBL with special focus on acquiring EBM principles.
Methods:
Two groups consisted of total 152 students (139 respectively). The use of EBM principles means integrating individual expertise with the best available external clinical evidence by using available data sources and national guidelines.
Conclusion:
Our findings suggest that modified PBL with extended EBM approach could be superior to "classical" PBL (Fig. 3, Ref. 29). Full Text (Free, PDF) www.bmj.sk.
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