Related Experiment Video
Updated: Jun 16, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Earlier parental set bedtimes as a protective factor against depression and suicidal ideation
James E Gangwisch1, Lindsay A Babiss, Dolores Malaspina
1Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10032, USA.
Study Objectives:
To examine the relationships between parental set bedtimes, sleep duration, and depression as a quasi-experiment to explore the potentially bidirectional relationship between short sleep duration and depression. Short sleep duration has been shown to precede depression, but this could be explained as a prodromal symptom of depression. Depression in an adolescent can affect his/her chosen bedtime, but it is less likely to affect a parent's chosen set bedtime which can establish a relatively stable upper limit that can directly affect sleep duration.
Design:
Multivariate cross-sectional analyses of the ADD Health using logistic regression.
Setting:
United States nationally representative, school-based, probability-based sample in 1994-96.
Participants:
Adolescents (n = 15,659) in grades 7 to 12.
Measurements And Results:
Adolescents with parental set bedtimes of midnight or later were 24% more likely to suffer from depression (OR = 1.24, 95% CI 1.04-1.49) and 20% more likely to have suicidal ideation (1.20, 1.01-1.41) than adolescents with parental set bedtimes of 10:00 PM or earlier, after controlling for covariates. Consistent with sleep duration and perception of getting enough sleep acting as mediators, the inclusion of these variables in the multivariate models appreciably attenuated the associations for depression (1.07, 0.88-1.30) and suicidal ideation (1.09, 0.92-1.29).
Conclusions:
The results from this study provide new evidence to strengthen the argument that short sleep duration could play a role in the etiology of depression. Earlier parental set bedtimes could therefore be protective against adolescent depression and suicidal ideation by lengthening sleep duration.
Related Concept Videos
Insufficient Sleep and Sleep Deprivation
Sleep deprivation is a more severe form of sleep loss...
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Relationship with Parents: Attachment
Nightmares and Night Terrors
Nightmares often...
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
