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Interleukin-6 positive follicular hyperplasia in the lymph node of a patient with rheumatoid arthritis
Y Numata1, Y Matsuura, S Onishi
11st Department of Internal Medicine, Kochi Medical School, Japan.
American Journal of Hematology
|April 1, 1991
Abstract:
We examined interleukin-6 production in the hyperplastic lymph node of a 77-year-old male rheumatoid arthritis patient with lymphadenopathy. The interleukin-6 production of the lymph node was observed by both immunohistological staining and in vitro culture. The results suggest that interleukin-6 plays a significant pathogenic role in the etiology of the lymphadenopathy seen in many rheumatoid arthritis patients.