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Noninfectious fever following aortic surgery: incidence, risk factors, and outcomes

Yun-tai Yao1, Li-huan Li, Qian Lei

  • 1Department of Anesthesiology, Fuwai Cardiovascular Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.

Chinese Medical Sciences Journal = Chung-Kuo I Hsueh K'O Hsueh Tsa Chih
|February 4, 2010
PubMed
Abstract

Insights

Noninfectious fever after aortic surgery is common, affecting 74.5% of patients. Key predictors include thoracic surgery site, lower intraoperative bladder temperature, and higher intensive care unit admission temperature.

Area of Science:

  • Cardiovascular Surgery
  • Critical Care Medicine
  • Surgical Oncology

Background:

  • Postoperative fever is a common complication following major surgical procedures.
  • Understanding the causes and risk factors for noninfectious fever after aortic surgery is crucial for patient management.

Purpose of the Study:

  • To investigate the incidence, clinical course, risk factors, and outcomes of noninfectious fever in patients undergoing aortic surgery.
  • To identify predictors of noninfectious postoperative fever in this patient population.

Main Methods:

  • Retrospective review of 463 patients who underwent aortic aneurysm or dissection surgery between January 2006 and January 2008.
  • Exclusion criteria included known infection sources, preoperative fever, emergency surgery, and incomplete data.
  • Univariate and multivariate logistic regression analyses were used to identify risk factors for noninfectious postoperative fever.

Main Results:

  • Noninfectious postoperative fever occurred in 74.5% of patients (345 out of 463).
  • Significant predictors for noninfectious fever included thoracic/thoracoabdominal surgical site (OR: 4.861), lower intraoperative bladder temperature (OR: 1.117), and higher intensive care unit (ICU) admission temperature (OR: 2.57).
  • No significant differences were observed in postoperative hospitalization duration or medical costs between febrile and afebrile patients.

Conclusions:

  • Noninfectious fever is a highly prevalent complication after aortic surgery.
  • Perioperative factors, particularly the surgical site and intraoperative/early postoperative temperatures, are closely associated with the development of noninfectious fever.

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