Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Humoral Immune Responses01:36

Humoral Immune Responses

Overview
What is the Immune System?01:38

What is the Immune System?

Overview
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
Immunological Memory01:23

Immunological Memory

Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature is...
Active versus Passive Immunity01:31

Active versus Passive Immunity

Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modifications of the Secretome of Mesenchymal Stromal Cells under Conditions of Stress-Induced Aging.

Bulletin of experimental biology and medicine·2025
Same author

The Level of Markers Stimulating Growth Factor 2 (ST2), N-Terminal Prohormone of Brain Natriuretic Peptide (NT-proBNP), and D-Dimer in Healthy Volunteer Testers in 21-Day Head-Down -6° Tilt Bed Rest as a Model of Hypodynamia.

Bulletin of experimental biology and medicine·2024
Same author

Influence of a Passive Tilt Test on the Proteomic Composition of the Blood of Healthy Humans.

Bulletin of experimental biology and medicine·2024
Same author

Correlation between proteome changes and synchrony of cardiac electrical excitation under 3-day «dry immersion» conditions.

Frontiers in physiology·2023
Same author

Changes in the body fluids proteome as a reflection of the physiological effects of dry immersion.

Frontiers in physiology·2023
Same author

[Age features of heart rate variability in cosmonauts according to urine proteomics data.]

Advances in gerontology = Uspekhi gerontologii·2023

Related Experiment Video

Updated: Jun 16, 2026

Murine Model of Epicutaneously-Induced Immunomodulation
09:07

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

[Human immunity system status during 7-day dry immersion].

T A Berendeeva, M P Rykova, E N Antropova

    Aviakosmicheskaia I Ekologicheskaia Meditsina = Aerospace and Environmental Medicine
    |February 4, 2010
    PubMed
    Summary

    Dry immersion significantly impacts immune function, reducing lymphocyte activity and cytokine production. Individual immune responses vary, indicating a predisposition to immune system changes in altered gravity.

    More Related Videos

    A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
    09:02

    A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

    Published on: June 7, 2017

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018

    Related Experiment Videos

    Last Updated: Jun 16, 2026

    Murine Model of Epicutaneously-Induced Immunomodulation
    09:07

    Murine Model of Epicutaneously-Induced Immunomodulation

    Published on: June 24, 2025

    A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
    09:02

    A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens

    Published on: June 7, 2017

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018

    Area of Science:

    • Immunology
    • Space Medicine
    • Physiology

    Background:

    • Understanding the human immune system's response to microgravity is crucial for astronaut health.
    • Dry immersion is a validated ground-based model for simulating microgravity effects.
    • Previous research indicates potential immune alterations during spaceflight.

    Purpose of the Study:

    • To investigate the effects of 7-day dry immersion on immune cell subpopulations.
    • To assess the activation potential of T-, B-, and NK-cells.
    • To analyze cytokine production by immunocompetent cells in peripheral blood.

    Main Methods:

    • Studied five healthy volunteers undergoing 7-day dry immersion.
    • Analyzed peripheral blood for lymphocyte subpopulations.
    • Assessed T-, B-, and NK-cell activation potential.
    • Measured cytokine production by immunocompetent cells.

    Main Results:

    • Observed significant negative shifts in immunity and cytokine production.
    • Demonstrated reduced activation potential in T-, B-, and NK-cells.
    • Highlighted considerable individual variability in immune responses.

    Conclusions:

    • Seven-day dry immersion without countermeasures negatively affects immune and cytokine systems.
    • Individual predisposition plays a role in immune system adaptation to altered gravity.
    • Further research is needed to understand and mitigate these immune changes for long-duration space missions.