["Jet-lag"--pathophysiology and methods of prevention and treatment]

Today's world enables quick travelling what may be connected with crossing multiple time zones. Numerous studies have shown that travelling across three or more time zones may lead tojet lag, which is a consequence of circadian misalignment that occurs after crossing time zones too rapidly for the circadian system to keep pace. The severity of symptoms and time of its maintenance rises with the number of time zones crossed and after eastward flights. A lot of techniques of light therapy and pharmacological treatment are being used in order to reduce the jet lag symptoms, however their effectiveness is still being questioned. Therefore, the awareness of travelers should be rised and they should be helped with the proper preparation to transmeridian flights, which may enable faster adaptation to a new time zone with the minimal use of pharmacology.