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Biologically active polypeptides in milk.

J R Britton1, A J Kastin

  • 1Veterans Administration Medical Center, New Orleans, Louisiana.

The American Journal of the Medical Sciences
|February 1, 1991
PubMed
Summary
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Milk contains biologically active polypeptides with proposed functions beyond nutrition for mothers and infants. Evidence suggests these polypeptides may play physiological roles in both maternal and infant health.

Area of Science:

  • Biochemistry
  • Lactation Biology
  • Developmental Biology

Background:

  • Milk from various species contains numerous biologically active polypeptides.
  • These milk-derived polypeptides are proposed to have functions beyond basic nutrition.
  • Their presence suggests potential roles in maternal and infant physiology.

Purpose of the Study:

  • To review the origins and functions of biologically active polypeptides in milk.
  • To explore the regulatory factors controlling their secretion and fate.
  • To consolidate evidence supporting their physiological significance.

Main Methods:

  • Literature review of studies on milk polypeptides.
  • Analysis of research on polypeptide secretion and metabolism.

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  • Synthesis of evidence regarding physiological functions.

    • Main Results:

    • Biologically active polypeptides are present in milk across species.
    • Multiple factors influence the secretion and biological fate of these polypeptides.
    • Evidence indicates these polypeptides may exert physiological effects.

    Conclusions:

    • Milk polypeptides possess diverse biological activities.
    • Their physiological roles in maternal and infant systems warrant further investigation.
    • Understanding these functions can advance nutritional and developmental science.