Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Potentiometry: Membrane Electrodes

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at the...

Osmosis and Osmotic Pressure of Solutions

Osmosis and Osmotic Pressure of Solutions

A number of natural and synthetic materials exhibit selective permeation, meaning that only molecules or ions of a certain size, shape, polarity, charge, and so forth, are capable of passing through (permeating) the material. Biological cell membranes provide elegant examples of selective permeation in nature, while dialysis tubing used to remove metabolic wastes from blood is a more simplistic technological example. Regardless of how they may be fabricated, these materials are generally...

The Resting Membrane Potential

The Resting Membrane Potential

Electrochemical Gradient and Channel Proteins: An Overview

Electrochemical Gradient and Channel Proteins: An Overview

An electrochemical gradient is a fundamental concept in biology and chemistry. It regulates the movement of ions across cell membranes. This movement is influenced by two factors:
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell. This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinical pathological analysis of primary small cell neuroendocrine carcinoma of the cervix: A retrospective study.

Medicine·2025

Same author

Potentiometric Studies on Ion-Transport Selectivity in Charged Gold Nanotubes.

Nanomaterials (Basel, Switzerland)·2024

Same author

Effect of Organic Cation Adsorption on Ion-Transport Selectivity in a Cation-Permselective Nanopore Membrane.

Langmuir : the ACS journal of surfaces and colloids·2024

Same author

MiR-371a-5p Positively Associates with Hepatocellular Carcinoma Malignancy but Sensitizes Cancer Cells to Oxaliplatin by Suppressing BECN1-Dependent Autophagy.

Life (Basel, Switzerland)·2022

Same author

The Ionic Composition and Chemistry of Nanopore-Confined Solutions.

ACS nano·2022

Same author

Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses.

Drug metabolism and disposition: the biological fate of chemicals·2021

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

Electroosmotic flow rectification in pyramidal-pore mica membranes.

Pu Jin¹, Hitomi Mukaibo, Lloyd P Horne

¹Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA.

Journal of the American Chemical Society

|February 4, 2010

Summary

We discovered Electroosmotic flow (EOF) rectification in synthetic membranes with asymmetric pores. This phenomenon, driven by ion current rectification, shows directional flow control, paving the way for advanced membrane technologies.

More Related Videos

Generation and Control of Electrohydrodynamic Flows in Aqueous Electrolyte Solutions

Generation and Control of Electrohydrodynamic Flows in Aqueous Electrolyte Solutions

Published on: September 7, 2018

Introduction to Solid Supported Membrane Based Electrophysiology

Introduction to Solid Supported Membrane Based Electrophysiology

Published on: May 11, 2013

Related Experiment Videos

Last Updated: Jun 16, 2026

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Published on: February 23, 2017

Generation and Control of Electrohydrodynamic Flows in Aqueous Electrolyte Solutions

Generation and Control of Electrohydrodynamic Flows in Aqueous Electrolyte Solutions

Published on: September 7, 2018

Introduction to Solid Supported Membrane Based Electrophysiology

Introduction to Solid Supported Membrane Based Electrophysiology

Published on: May 11, 2013

Area of Science:

Electrokinetics
Materials Science
Nanotechnology

Background:

Electroosmotic flow (EOF) is a key electrokinetic phenomenon used in microfluidics and separation sciences.
Asymmetric pore structures are crucial for developing functional membranes with directional transport properties.

Purpose of the Study:

To demonstrate and characterize a novel electrokinetic phenomenon: Electroosmotic flow (EOF) rectification.
To investigate the influence of pore asymmetry on EOF behavior under ionic current.
To elucidate the underlying mechanism of EOF rectification in synthetic membranes.

Main Methods:

Fabrication of synthetic mica membranes with precisely engineered asymmetric, pyramidally shaped pores using the track-etch method.
Application of a constant ionic current across the membranes to drive EOF.
Systematic measurement and analysis of EOF velocity under varying current polarities.

Main Results:

Demonstrated significant EOF rectification in asymmetric-pore membranes, where flow velocity is dependent on current polarity.
Observed higher EOF velocity when flow was directed from the pore's larger base to its smaller tip.
Identified ion current rectification as the fundamental mechanism responsible for the observed EOF rectification phenomenon.

Conclusions:

The study successfully demonstrates EOF rectification in synthetic asymmetric-pore membranes.
The findings highlight the critical role of pore geometry in controlling electrokinetic transport.
This work provides a foundation for designing advanced membranes with tunable flow characteristics for various applications.