Related Experiment Video

Updated: Jun 16, 2026

A Rat Model of Compound Acne
03:10

A Rat Model of Compound Acne

Published on: November 1, 2024

Massive ascites as unique sign of shunt infection by Propionibacterium acnes

Nicola Montano1, Carmelo Sturiale, Giovanna Paternoster

  • 1Institute of Neurosurgery, Catholic University, Rome. nicolamontanomd@yahoo.it

Insights

Propionibacterium acnes shunt infections typically present with mild symptoms. This case highlights massive ascites as a unique sign of cerebrospinal fluid infection in a patient with P. acnes shunt infection.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Propionibacterium acnes (P. acnes) is a known pathogen implicated in shunt infections.
  • Shunt infections often manifest with subtle or mild clinical signs.

Observation:

  • A case of P. acnes shunt infection is presented.
  • The infection uniquely manifested with massive ascites, mimicking a sign of cerebrospinal fluid (CSF) infection.

Findings:

  • The patient experienced massive ascites as the sole indicator of CSF infection.
  • Treatment involved shunt removal, antibiotic therapy, and ascites drainage.

Implications:

  • This case expands the spectrum of clinical presentations for P. acnes shunt infections.
  • Highlights the importance of considering atypical presentations, such as massive ascites, in shunt infections.
  • Suggests prompt intervention including surgical removal, antibiotics, and ascites management leads to rapid recovery.

Related Concept Videos

Ascites01:19

Ascites

DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...