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Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Updated: Jun 16, 2026

Rabies Necropsy Techniques in Large and Small Animals
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Rabies Necropsy Techniques in Large and Small Animals

Published on: July 30, 2019

[Rabbit fever--a neck tumor].

Karianne Høstmark1, Janko Moritz

  • 1Sygehus Syd, Region Sjaelland, Øre-nase-halsafdelingen, Denmark. kariannehos@gmail.com

Ugeskrift for Laeger
|February 4, 2010
PubMed
Summary
This summary is machine-generated.

A previously healthy animal caretaker developed a neck tumor caused by Francisella tularensis (F. tularensis). Early diagnosis and ciprofloxacin treatment led to a decrease in F. tularensis titers.

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Tularemia is a zoonotic disease caused by Francisella tularensis.
  • Occupational exposure in animal handlers is a known risk factor.
  • Neck tumors can present as an unusual manifestation of tularemia.

Observation:

  • A previously healthy 22-year-old male animal caretaker presented with a neck tumor.
  • Initial examination revealed necrotic lymphadenitis, with negative primary serology.
  • The patient later tested positive for F. tularensis.

Findings:

  • The patient was successfully treated with oral ciprofloxacin (750 mg twice daily for two weeks).
  • Treatment resulted in a significant reduction in F. tularensis titers within seven weeks.
  • This case highlights the importance of considering tularemia in the differential diagnosis of neck masses in at-risk individuals.

Implications:

  • Prompt diagnosis and appropriate antibiotic therapy are crucial for managing tularemia.
  • This case underscores the zoonotic potential of F. tularensis and the need for vigilance in occupational health.
  • Effective treatment protocols can lead to favorable patient outcomes, even with atypical presentations.