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Updated: Jun 16, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
Are transition zone biopsies necessary in transrectal ultrasound-guided transperineal prostate biopsy protocol?
Zhu Yunkai1, Chen Yaqing, Wang Ren
1Department of Ultrasound in Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, PR China.
Purpose:
The purpose of this study was to determine the utility of routine transperineal transition zone (TZ) biopsies.
Materials And Methods:
A total of 1028 consecutive patients underwent transrectal ultrasound-guided prostate biopsies for the first time. Sextant biopsies and additional two-core TZ biopsies were performed.
Results:
Prostate cancer detection rate was increased by sampling two additional cores from TZ.
Conclusions:
Transition zone biopsies might be reserved to improve the detection rate of prostate cancer in transperineal biopsy protocol.
